Doesn’t appear to.
But looks like even GNOME Web supports extensions now. So no reason that something like uBlock origin couldn’t be implemented right?
When I last tried it (around the time that article was posted, could’ve improved since), you needed to mess with gconf to enable the feature, which was for good reason because the compatibility was abysmal (ublock origin did not work and neither did dark reader or violentmonkey or really any extension I wanted to use).