From my understanding, they are most likely just blocking the defualt port of wireguard / openvpn and IPs associated with the VPN servers of VPN providers they dont like.
If they wanted to block VPN traffic over 443 to any IP, they would have to do deep packet inspection, which I would imagine is infeasible for Russia.
Supposedly, the Chinese great firewall does use deep packet inspection, so it is possible to do this at the country level.
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