I’m currently testing Fedora KDE on a VM (windows host) before eventually switching over to Linux completely.
Tbh youre probably better off on something like Linux Mint or something else Debian or Ubuntu based. Fedora is a good distro but rpms are a lot less common than debs are and alien does not entirely fix that issue.
While I would still recommend Ubuntu or Mint or even Debian, I have been using openSUSE for years and have never run into a case where I had to compile software.
I’m not sure why you are bringing Gentoo into it here. I mean that all the software I have tried to install is either available in the repos or available as an appimage/flatpak. Were it not available in binary form I would need to compile it - and I have not run into that scenario.