He might still fit because you would think clark Kent’s humour would be very dry and mostly rely on timing. The contrast would be great having the silliness come from the CIA characters who could be extremely animated and frustrated. I can only imagine the scenes about the CIA agents trying to explain to their boss why they keep failing
Directed by Wes Anderson, with Jason Schwartzman playing Superman/Clark Kent, Saoirse Ronan as Lois Lane, Bill Murray playing Perry White, and Owen Wilson as Luthor. CIA boss played by Jeff Goldblum, vice-President of the USA played by Anjelica Huston, and President not seen on-screen but voice acted by Ira Glass.