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205 points

It’s catch and release so they let them go afterwards where they found them. Horseshoe crab blood is an essential biomedical tool that’s saved countless lives.

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80 points

What are some example uses for the blood? I’m fascinated.

Thanks for the reply too.

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23 points
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The main use is to detect how much endotoxins (proteins that cause our immune system to react) are present in a sample. This is important because we often use bacteria/fungus/yeast to produce medicine and then remove the microorganism from that medicine. This checks for anything left behind in that process, far more sensitive than any other test or machine can do.

If it wasn’t for horseshoe crab blood, creating medicine that is safe for injection would be a lot harder and potentially more dangerous.

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7 points

Wonder why we can’t just make the coagulant ourselves. Or maybe we can but milking crabs is still cheaper.

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38 points

The blood contains a coagulent which clots in the presence of bacterial toxins. It is extracted and used to ensure that medical equipent and stuff such as vaccines are sterile and safe.

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10 points
134 points

It’s an anticoagulant and can detect the smallest traces of endotoxins in medicine. I’m sure I’m missing some details but there are some great medical journals that detail the process and help explain why it’s $60,000 a gallon.

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36 points

Where can someone find these horseshoe crabs?

And are they able to be bred in captivity?

Pls respond fast, I’m already driving to home depot to buy the largest above ground pool they have.

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47 points

It is not an anticoagulant, quite the opposite actually. The blood (limulus amoebocyte lysate) will coagulate at the slightest hint of gram-negative bacteria and their endotoxins.

It’s most likely a defense mechanism against bacterial infections.

It’s widely used in medicine to check for bacterial contamination of injectable pharmaceuticals.

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76 points

$15.85 per ml, for a more at scale measurement.

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