If you want to pedestrianize it, then every casino along it will have to reroute whatever roads through their property to the roads behind them.

The casinos on the strip already all have back/off-street entrances, it’s where most of the parking is. You’d still allow east/west traffic on the major roads like Flamingo and Tropicana, and if they really want to keep those front entrances they could retrofit them to run trams up to them. They could even have a different tacky tram for each hotel or something.

If they’re super concerned about losing the ‘freedom’ to drive down the strip then they could have select hours where they open it to (some) cars like how they periodically close it for pedestrians now for things like New Years and whatnot.