As long as whatever is on the other end doesn’t reproduce anything at 60Hz or does so with a lot of loss and there are no heavy vibrations closeby (such as the speakers themselves), it should be fine.
Why 60 Hz? Doesn’t the frequency response of this antenna depend on the length/shape?
It’s the one part of the radio spectrum that’s also in the hearing range hence induced currents from it can be heard in an analog audio system and which would have a pretty decent amount of energy inside a building because it’s being emitted pretty much all around by the mains power wires.
That said, you’re right that depending on the length and shape those wires might not form a very good antenna for that frequency. Independently of that, I doubt there’s enough energy around to directly affect speakers, but it might be enough if that wire goes to an amplifier which in turn powers the speakes.
That said, I’m from Digital Systems rather than Telecomms or Audio so take what I say on this as a semi-informed guess.
It does have a decent loop area in between the signal and return path and any flux passing through it will induce noise. This area is too small for 60 Hz, but there’s a lot of microwave crap that would get picked up. If there isn’t a low-pass analog filter before the next silicon junction then this RF EMI will get rectified down. If it’s a sufficiently bad situation then you’ll hear it. That’s why you can hear garbage when you put your phone right next to crappy computer speakers.
