Kind of like how Metroid forked into its 2D and 3D incarnations
Most people use Zelda as their example for the phenomenon
I would be surprised to see another mainline 2D Zelda though, Zelda has pretty much been 3D since OOT except for the DS games.
Metroid had gone the same way and that’s why Dread was such a surprise to see and I feel like top down GTA would be the same sort of thing.
I doubt we will see something like Dread from the Zelda series after BotW/TotK were such expansive open worlds, Zelda just seems to be getting bigger.