From forming bound states to normal scattering, many possibilities abound for matter-antimatter interactions. So why do they annihilate? There’s a quantum reason we simply can’t avoid.
There aren’t. Even in “empty” space, there’s about one atom per cubic meter, enough for a small amount of annihilation. We haven’t detected any regions bordered by gamma ray emissions that would indicate a matter-antimatter boundary.
https://en.wikipedia.org/wiki/Baryon_asymmetry#Regions_of_the_universe_where_antimatter_dominates