9 points
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I wish there were some link to the study in the article, I tried to find it in the original Financial Times article but I got paywalled. This is really awesome though, I hope further research is shown because I’d love to hear more about how this differs from the previous methods of addressing Alzheimer’s.

I guess

Both lecanemab and donanemab are based on antibodies against amyloid, one of the toxic proteins that build up in the brain as Alzheimer’s proceeds, but they worked at different stages of the process, Oakley said. Lecanemab targets amyloid as it begins to form fibers in the brain while donanemab is active at a later stage, when the fibers have clumped together into larger accumulations of plaque.

Is as close as we’re getting for now haha

Edit: TheOakTree found the study for those who want to read more!

Direct link to study.

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8 points

https://jamanetwork.com/journals/jama/fullarticle/2807533

Not exactly what you were looking for (I think) but closer!

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5 points

From the Ars Article:

The donanemab trial involved 1,736 participants

From your link:

Findings In this randomized clinical trial that included 1736 participants with early symptomatic Alzheimer disease and…

I would be VERY surprised if this wasn’t the study in question 😂

Thank you for finding that! I’ll read that over more when I get some time later!

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4 points

Now imagine if it were coincidence…

Thankfully it’s not. Happy to see that alzheimer research is getting more interest though, it’s a scary condition.

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4 points

The article mentions the donanemab study was published in JAMA. A little bit of Googling retrieved this:

https://jamanetwork.com/journals/jama/fullarticle/2807533

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1 point
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Yup, you’re an hour late to that convo haha

I’ll edit my original comment so others see that though.

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1 point

Weird, that comment definitely wasn’t visible to me when I replied. Must be the magic of federation…

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5 points

extremely promising! awesome to see

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4 points

Finally some good fucking news. Wish we had the article, though.

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3 points
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