An interesting paper describing a eukaryote native RNA-guided endonuclease, like CRISPR. Seems less efficient at the moment, but it the scientific community gets behind it and starts developing the methods, it may superseded the efficacy of CRISPR in eukaryotic cells.

The Paper:

https://www.nature.com/articles/s41586-023-06356-2

(unfortunately not available on SciHub https://sci-hub.st/https://www.nature.com/articles/s41586-023-06356-2 )

If you want a copy of the paper, secure DM (matrix).

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