4 points

How to invoke tldr bot?

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10 points

It automatically replies when it can read/summarize a site, but that isn’t always possible (maybe it has problems with some paywalls).

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54 points
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Gene filtering for IVF babies… gattaca

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18 points

Glad I wasn’t the only one who thought of that

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2 points

Is there a nonpaywall link?

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9 points

Check comments, it has been posted.

You can also visit an archive website and paste url on search bar.

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125 points

Jack be nimble, Jack be quick, Jack jump over the paywall click: https://archive.is/8WWq2

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14 points
*

Link didn’t work for me but suck such a nice wording

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7 points

suck a nice wording

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3 points

I love to suck nice wordings

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2 points

Weird, just checked and it still works for me.

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1 point

It works for me now, guess it was just down.

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1 point

I guess the server is crushed. I don’t understand modern webpage development and web servers at all. 25 years ago I hosted 10,000 simultaneous connections on 4 megabit line (part of a t3) and a Pentium 3 server. It was fast.

The link is text with a picture. It should be a couple dozen kilobytes. A 10 year old PC on a home 100mbs Internet service should handle hundreds of simultaneous connections.

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26 points

How much does an Orchid screening cost?

It’s $2,500 per embryo.

And presumably you’d be screening several embryos. What about for families that can’t afford that?

We have a philanthropic program, so people can apply to that, and we’re excited to accept as many cases as we can.


I must now ask a question I’ve been dreading. I’m sorry in advance. Here goes. It’s the inevitable question about Theranos and Elizabeth Holmes.

No, this is the worst question. This is so mean.

Tell me why it’s so mean.

I find it sad. It’s a sad state of affairs where—my friends who aren’t even in health, they say they get it too. It’s like, any female CEO with any tech-adjacent thing is constantly being questioned—by the way, are you like this other fraud? Do you want to comment on this other random fraud that occurred that has absolutely nothing to do with you besides the person being the same gender as you?

If you’re trying to charitably understand where this question is coming from, how do you do that?

What would be the charitable interpretation—besides that our society is incredibly misogynistic and men’s frauds and failings are passed aside and when one female does it she stands for every other female CEO ever?

So there’s no charitable interpretation.

I don’t think there is. Society treats men as, like, default credible. For a woman, the default is skeptical.

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22 points

They could just ask who has verified the outcomes… No need to do the ‘are you a fraud’ line

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31 points

It’s like, any female CEO with any tech-adjacent thing is constantly being questioned—by the way, are you like this other fraud?

This really sounds like she is admitting that this is fraud, and that she doesn’t like being compared to other fraud.

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16 points
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Yeah, she didn’t really address fraud comparisons. Went straight to sexism. Both can be true, and if you are a CEO of a medical company you should be ready to prove your shit works.

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7 points
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If I (man) was being interviewed and the interviewer randomly said “hey, I read in the news a little while ago that a man committed fraud, and well, you’re a man too. Are you a fraud?”, I also wouldn’t dignify it with a response.

If the interviewer had said “This seems like a service a lot of people would want to partake in - how has the efficacy of this procedure has been confirmed, how can we verify that it works?”, he’d have got an answer.

Saying “hey, these people with no link to you other than your genitals are frauds, and it makes me feel like you could be, so are you?” doesn’t deserve to be treated like a question asked in good faith, because it isn’t.

E: spelling

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-1 points

Wtf? No. What relevance does theranos have to this company? Does the interviewer ask the same thing to any other bio tech CEO?

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10 points
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The reason people are comparing her bullshit made up science crap to Theranos is because she is not a medical person promoting a medical thing that supposedly checks for thousands of times more things than established science with a minuscule sample. Somehow this caught on in a ton of places through being the new hotness and will most likely implode when it is proven to be snake oil in less than a decade.

This is the exact same situation as Theranos.

Plenty of existing companies, like 23andMe, already screen for BRCA variants.

23andMe does an array. They only look at, I think, 44 BRCA variants of the 70,000. If you only look at a few, then you can give people false certainty.

And they’re obviously not testing embryos.

Yeah, they just do people.

Whereas you sequence the entire genome of embryos—orders of magnitude more information, on both monogenic and polygenic conditions, than anything that’s ever been done before. Even your main competitor, Genomic Prediction, only does arrays of embryos, looking for specific things.

Yeah. Whole genome is a big deal and a massive upgrade. You can mitigate risks for thousands of diseases that previously you weren’t able to detect. It’s kind of like a vaccine for everything that we know, genetic-wise, at once.

And all off a very small amount of DNA.

About 5 picograms per cell in an embryo sample. That’s a really, really tiny amount. From both a chemistry perspective and a computational perspective, we had to invent new things to make it so that you can recover whole-genome data.

It’s fucking tech bro bullshit, and the fact that she shares a gender with the other high profile person is a coincidence. While there is something to be said about not pushing back on the men doing the same thing, the criticism of her totally not eugenics because it involves computers logic is completely warranted and the comparison is spot on.

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4 points

That “other” is the possible Freudian slip.

But she does have somewhat of a point. Though it’s female and tech and medical - a closer comparison - women in tech leadership roles do get more questioned on their competence than do men.

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1 point

I think it’s that in the questioner’s mind, they have decided she is a fraud, and want to know if she’s like the other one.

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