19 points
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“The JCU trial provides sufficient proof of concept that infection with live hookworms is safe and appears to have some sort of beneficial effects on people’s metabolic health, which will hopefully be confirmed by future clinical trials designed to confirm efficacy and explore how hookworms influence metabolism,” said Dr Paul Giacomin, AITHM Senior Research Fellow and immunologist.

Eat less vs feed a crop of worms in my guts…. Hmmmmm. I mean, it’s an efficient way of making sure you don’t absorb all the calories you consume. It would be a bummer if my worms’ eggs were infecting people who didn’t over-eat and would be harmed.

The anti-inflammatory aspect is intriguing, but there has to be better options for creating that response.

This “give you worms so you can continue to overeat without consequences” approach is far too reminiscent of the ancient Roman vomitoria. There has to be a less wasteful way to deal with obesity and its metabolic consequences.

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14 points

FYI, as per the other commentor, vomitariums are a myth.

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1 point

Yup. No worries. Still don’t like the idea of having worms.

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2 points

Fortunately, nobody is judging you for that sentiment quite as hard as you were judging people for studying nutritional health after not really reading the article.

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2 points

Vomitoria existed, but they were used for people to leave a stadium, not for food to leave the stomach.

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1 point

Yes, I know. I was addressing it in the context of OP

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6 points

who the fuck went “yeah, ima get some dangerous parasites into my guts” how much money did they get for that

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3 points

I sustained myself for 6 months on nothing but being a medical Guinea pig. Because of anonymity laws they couldn’t ask for documentation so it was one of the few gigs I could do without a work permit. I would have loved this experiment, sure as hell beat the “let’s inject pepper under your skin and give you the placebo painkiller” trial I did for three painful weeks (paid $2800 though).

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Enough to pay for half their insulin for the month?

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6 points

australias healthcare system cant be as abysmally bad as america…right?..right?

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4 points

The difference between medicine and poison is the dose. The worms were not dangerous at the dose being studied, as indicated by the fact people got healthier over a 2 year period.

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2 points

sure but idk living parasites seem like part of an equation id rather remove

wanna go back to leech treatments? maybe tapeworms too to loose some weight?

it just seems to volatile

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2 points

Leeches are still used, and are very effective in some cases. It’s ok to be grossed out by medicine. That doesn’t mean it’s outdated or shouldn’t exist.

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5 points

satan! I read it looking to see how they modified the hookworms and I can’t find anything outside of saying they were farmed and lab grown. We do so much de-worming with animals and now im wondering if that is bad for them???

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9 points

De-worming animals is probably still for the best. Even hookworms can be fatal to dogs, for example. And there are other worm parasites way worse than hookworms, like roundworms that can burrow through the intestines and up into the host’s heart and brain. I wouldn’t take the risk.

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6 points

yeah I was just musing and reading the whole paper the participants had some initial gastro intestinal issues for a day or so from getting the worms. seems its basically a very small dose of them can be beneficial so you totally don’t want to get them naturally.

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3 points

Hook me up!

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1 point

It makes sense. Having worms has been a constant across human history, so if we need to bring dirt back to prevent allergies maybe we should all have these guys too.

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