Like Fluoride or Oxygen.

69 points

Just about anything including water or salt

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48 points

Not just about. Literally everything is lethal at a high enough concentration.

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19 points
5 points

Alle Dinge sind Gift, und nichts ist ohne Gift; allein die Dosis macht, dass ein Ding kein Gift ist.

All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison.

Paracelsus, 1538

The word for poison in German is Gift?!

The word has been used as a euphemism for “poison” since Old High German, a semantic loan from Late Latin dosis (“dose”), from Ancient Greek δόσις (dósis, “gift; dose of medicine”). The original meaning “gift” has disappeared in contemporary Standard German, but remains in some compounds (see Mitgift). Compare also Dutch gift (“gift”) alongside gif (“poison”).

Well that’s dumb.

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5 points

The first part of the question asks what is safe in small amounts

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4 points

I’d argue gravitational force isn’t lethal. As long as you don’t arrive at whatever is pulling you & the gradient of gravity doesn’t change across your body length. You could be perfectly fine (for a while) orbiting a black hole at enormous speeds (assuming you don’t collide with matter in the accretion disc.

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16 points

I’d argue against that. For one thing it is impossible to imagine a situation where there is no change in the gravitational gradient across your body over time. Your orbiting a black hole situation is a perfect example of a situation where the gradient alone would tear you apart. The conditions you’ve specified are tautological. There’s no way to maintain a zero gravitational gradient while also simultaneously having extremely high gravitational field. The two are mutually exclusive in any conceivable scenario.

It’s like saying a human being in a hypersonic wind stream won’t necessarily hurt you, burn you alive and rip you to pieces (not necessarily in that order) as long as there is no turbulence and you have a sufficient boundary layer – but you’re a non-aerodynamic human body in a hypersonic wind stream, so of course there will be turbulence and the boundary layer will not protect you at all, you’re going to die, basically instantly.

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3 points

You argue that it isn’t, and then provide several examples where it is.

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2 points

I think General Relativity is based on the idea that a frame of reference that’s in freefall is equivalent to one that in a gravity free region of space (at least that was one of Einstein’s Gedankenexperiments that led him to his theory of GR).

Having said that, in reality a sufficiently strong gravitational field will cause a tidal effect, which will crush you along one axis and pull you apart along another.

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1 point

Wouldn’t a high enough force cause the gradient of gravity to differ?

Unless I misunderstood how that works. I’m picturing a downed powerline that causes large differences in voltage across the ground, which is why you are supposed to shuffle instead of taking a normal step. Would a high enough gravity cause a harmful gradient across the length of a human body?

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2 points

I thought about this a bit and concluded that it only applies to physical materials and forces.

For example: There certainly are lethal ideas, but most of them are not, and much like bosons they can overlap, so filling a person with multiple copies of the same (benign) thought has a diminishing effect.

But yeah, anything physical has a lethal concentration.

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3 points

I love nerds.

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42 points
*

Panadol / Paracetamol / Tylenol / Acetaminophen / C8H9NO2 is exceptionally easy to overdose on. I’ve done it accidentally a couple of times. It causes liver damage at even lower overdoses, you really don’t want that.

The maximum dosage is 1g every 4 to 6 hours, maximum total 4g a day. I am no doctor but I strongly recommend 6+ hours between doses (I set a timer) and I try very hard to not get to 3g or above per day. It’s even worse that plenty of medications just throw it in to the mix casually.

Unfortunately as the only first line of defence I have against pain, I cannot avoid it altogether. Redflags for me were light abdominal pain and yellowing of skin under eyes. Plus fatigue, but that’s normal in my world.

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16 points

Huh. That might explain the last two weeks. Dental pains. Lot’s of tylenol. And why I feel much better now.

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12 points

For dental pain I recommend ibuprofen (advil). Seems to work significantly better than acetaminophen (Tylenol) and seems to be much safer.

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7 points

Some people can’t take NSAIDs unfortunately

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7 points

I was dual wielding.

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5 points

NSAIDs can be just as bad in different ways. They cause your digestive tract to bleed and can cause perforations.

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5 points
*

Tylenol can be taken with ibuprofen to increase pain or fever relief. Just follow directions for both.

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1 point

Definitely ease up on it if you can, especially if you’ve been taking it for more than a week regularly. If you can’t reduce usage/dose, then be much more generous with the minimum gap between doses, especially if your liver is already under a bit of pressure from other meds or alcohol.

Pain sucks, and pain management causes pain. Sorry about the dental stuff, my issue isn’t teeth but I know that is no fun too.

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3 points

I accidentally overdosed on acetaminophen after a surgery once. Doctor forgot to tell me (or I was still high when he told me) he gave me acetaminophen during/after the surgery. I thought I still could take up to 4g that day. A few hours after the surgery, the pain started to kick in so I took some acetaminophen. Ended up vomiting uncontrollably.

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1 point

Can you not use ibuprofen?

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3 points

Sadly no, the entire NSAID class are off the table. I’m one of the “lucky” few who gets one of the rare but serious side effects.

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36 points

Weed. A gram will get you high. A woolpack full of it can crush you like a grape if falling from the hay loft.

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10 points
woolpack
From Middle English wolpak, wullepak, equivalent to wool +‎ pack. 
A bag of wool, traditionally weighing 240 pounds.

TIL, Thx

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2 points
1 point

Woolie Nelson

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33 points

According to people I know, I’m only ok in small doses.

Then they leave.

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12 points

So you’ve never had so far the opportunity to test whether or not you are lethal at higher doses ?

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6 points

I think we have a volunteer

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32 points

Took a Hazmat class today and the big thing they drilled into our heads was “Everything is toxic at scale.” So make anything you want and there is an IDLH concentration.

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