Universal Paperclips is one of the best clicker games.

In particular: because it isn’t a clicker game. It only starts off as one. There’s only about 2 sections IIRC that are “clicker”, the start (before auto-clippers kick in), and then the quantum computer.

I guess you have to launch your first 20 or 30 probes at the space stage and that’s done one-click-at-a-time… but I don’t think that counts as a “clicker” game since its so few clicks in the great scheme of things. At no other point is rapid-clicking that useful.